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Sleep study seeks people with Parkinson's and/or RBD

Sleep study seeks people with Parkinson's and/or RBD

Posted 14/11/2018

Researchers at OPDC are embarking on a new five-year study looking at the links between a condition known as Rapid Eye Movement Sleep Behaviour Disorder (RBD) and Parkinson’s. Funded by the NIHR Oxford Biomedical Research Centre. The study seeks to improve the remote diagnosis and monitoring of sleep problems at home and is currently looking for people with Parkinson's and RBD to take part. RBD is a sleep problem where the switch that ...

Experimental cancer drug shows promise for Parkinson’s

Experimental cancer drug shows promise for Parkinson’s

Posted 29/11/2018

A drug originally developed for prostate cancer may have exciting potential for treating Parkinson’s, according to our new research published in Cell Stem Cell. The study, funded by Parkinson’s UK, suggests that the drug, tasquinimod, which is not yet on the market, works by controlling genes that may cause Parkinson’s. This happens when the drug interacts with a protein inside brain cells. The team here at the Oxford Parkinson’s Disease ...

Precision medicine for Parkinson’s, how close are we?

Precision medicine for Parkinson’s, how close are we?

Posted 28/11/2018

OPDC Medical statistician Michael Lawton has been working on a collaboration with the OPDC and Tracking Parkinson's cohorts to better define Parkinson's. His research has revealed 4 possible subtypes of the condition.

2018 OPDC Talks

2018 OPDC Talks

Posted 26/11/2018

We are pleased to annouced you can now watch the talks from the 2018 OPDC Participant's day online. The presentations, from September 10th, 2018 cover a range of subjects including our interest the link between sleep and Parkinson's, Parkinson’s dyskinesia, and drug discovery. We also welcomed Djordje Gveric from the Parkinson's UK Brain bank to tell us about the process and it's value.  Watch the talks  

One common variation in genetics can increase Parkinson’s risk

One common variation in genetics can increase Parkinson’s risk

Posted 09/11/2018

Work with OPDC from a DPhil project supported by the Oxford branch of Parkinson’s UK has been published in the journal Stem Cell Reports. The project, carried out under the supervision of OPDC’s Richard Wade-Martins focussed on the MAPT (microtubule-associated protein tau) gene, which provides the code for a set of six proteins called ‘tau’, and each of these six tau proteins is made from a different messenger RNA transcript made from the MAPT ...

Apathy in REM sleep behaviour disorder

Apathy in REM sleep behaviour disorder

Posted 02/11/2018

Last year, we published a paper showing that apathy is very common in people with idiopathic REM sleep behaviour disorder (RBD), and we have now followed this up with a brain imaging study that sheds light on why this is. Apathy is a condition where people feel a sense of indifference to doing activities or being with other people. It is very common in people with Parkinson’s and can have a severe effect on their lives and those of their ...

Impulse Control Behaviours and Creativity in Parkinson’s

Watch Mark Kelly's Parkinson Voice Project lecture presented in the Clark and Brigid Lund Parkinson's Education Center. Dr. Mark Kelly is a researcher at the Oxford Parkinson’s Disease Centre. He qualified at Trinity College Dublin and is currently training in general medicine with a keen interest in neurology and Parkinson’s disease. His research with the Oxford Discovery Project, led by Professor Michele Hu, focuses on the side effects of ...

Pete Magill welcomes Lord O’Shaughnessy

Pete Magill welcomes Lord O’Shaughnessy

Posted 18/10/2018

The Medical Research Council Brain Network Dynamics Unit at the University of Oxford recently welcomed Lord James O’Shaughnessy, Parliamentary Under-Secretary of State for Health, for a site visit organised as part of The Royal Society’s Pairing Scheme that OPDC theme 3 co-lead Professor Pete Magill is taking part in. The visit began with Unit Group Leaders Peter Brown, Peter Magill and Tim Denison highlighting why, how and where the Unit ...

OPDC Smartphone app tests for early signs of Parkinson's

OPDC Smartphone app tests for early signs of Parkinson's

Posted 04/10/2018

Parkinson’s is the second most common neurodegenerative disease, the hallmarks of which include tremor, stiffness, and slowness of movement. Existing tests for the assessment of Parkinson's require in-clinic examination. This can sometimes cause a delay in diagnosis. It is believed that there are changes in the brain 5 to 10 years before the symptoms of Parkinson's become evident. To try and facilitate early diagnosis of Parkinson's, we at the ...

OPDC welcomes Participants to Open Day

OPDC welcomes Participants to Open Day

Posted 21/09/2018

On September 10th,  2018 over 200 members of Discovery cohort came to the Jury’s Inn, Oxford to hear about our latest research and share their views. We would like to thank all of the cohort members who came to the event from our centres across the country, and joined in the lively discussion session. Researchers from across OPDC’s themes shared their work. These included talks on our work to develop a new test for Parkinson’s, how we are using ...