The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.
Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.
Our programme targets the molecular pathways to Parkinson’s in order to:
Rolinski M, Griffanti L, Piccini P, Roussakis AA, Szewczyk-Krolikowski K, Menke RA, Quinnell T, Zaiwalla Z, Klein JC, Mackay CE, Hu MT. (2016) Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson's disease. Brain. PMID: 27297241
Baig F, Lawton MA, Rolinski M, Ruffmann C, Klein JC, Nithi K, Okai D, Ben-Shlomo Y, Hu MTM. (2017) Personality and addictive behaviours in early Parkinson’s disease and REM sleep behavior disorder. Park Rel Dis. 37:72-78. PMID:28173973
On Monday 10th September, please join us for a FREE open afternoon of talks by our OPDC scientists and clinicians. Find out how your participation in the Discovery Cohort is improving our understanding of Parkinson's and driving us closer to a cure.
In 2014, the James Lind Alliance and Parkinson’s UK set up a Patient Setting Priority group to find the top 10 research priorities that people living with Parkinson’s (PwP) and health and social care professionals would like to see answered. This was published in 2014 by Deane et al. The aim was to use this information to guide future research and make sure researchers focus on the most urgent needs of people affected by Parkinson’s. At an OPDC ...
Professor Stephanie Cragg is the co-lead of theme 3 in OPDC and was recently invited to give the The European Journal of Neuroscience special lecture at the 2018 FENS Forum in Berlin, Germany, where she spoke on Trees and gates: Dopamine axon arbours as filters of dopamine output. Professor Cragg was also interviewed for a profile in the journal. Follow this link for the full article. A video interview with Professor Cragg can also be ...Click here to sign up to the OPDC News Mailing list
Behaviour and synaptic plasticity in a model of early Parkinson's: the role of alpha-synuclein Associate Professor and Head of Laboratory of Experimental Neurophysiology, IRCCS San Raffaele University, Rome, Italy. Dr Picconi has spent much of her career studying the alterations of synaptic plasticity in different models of neurodegenerative disorders, particularly in Parkinson's. Her research has focused on the study of the molecular and ...
The 2018 OPDC Research Day will be held in the Medical Sciences Teaching Centre, Oxford. The day will start at 9am with a day of talks and poster sessions on Parkinson's research. This will be followed by a drinks reception from 5-7pm. Attendance is free, but registration is required via our research day website. Abstract Submission closes Friday September 14th 2018