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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
  • Watch the video below to learn more about OPDC's research

 

Selected Publications

News

OPDC Participant's Open Day 2018

OPDC Participant's Open Day 2018

Posted 20/07/2018

On Monday 10th September, please join us for a FREE open afternoon of talks by our OPDC scientists and clinicians. Find out how your participation in the Discovery Cohort is improving our understanding of Parkinson's and driving us closer to a cure.


Getting to the Heart of Your Unanswered Research Questions

Getting to the Heart of Your Unanswered Research Questions

Posted 28/08/2018

In 2014, the James Lind Alliance and Parkinson’s UK set up a Patient Setting Priority group to find the top 10 research priorities that people living with Parkinson’s (PwP) and health and social care professionals would like to see answered. This was published in 2014 by Deane et al. The aim was to use this information to guide future research and make sure researchers focus on the most urgent needs of people affected by Parkinson’s. At an OPDC ...


Profiles of Women in Science: Prof. Stephanie Cragg

Profiles of Women in Science: Prof. Stephanie Cragg

Posted 20/07/2018

Professor Stephanie Cragg is the co-lead of theme 3 in OPDC and was recently invited to give the The European Journal of Neuroscience special lecture at the 2018 FENS Forum in Berlin, Germany, where she spoke on Trees and gates: Dopamine axon arbours as filters of dopamine output. Professor Cragg was also interviewed for a profile in the journal. Follow this link for the full article.   A video interview with Professor Cragg can also be ...

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Seminars/Events

Barbara Picconi 18 Sept 2018

Barbara Picconi 18 Sept 2018

Posted 20/07/2018

Behaviour and synaptic plasticity in a model of early Parkinson's: the role of alpha-synuclein Associate Professor and Head of Laboratory of Experimental Neurophysiology, IRCCS San Raffaele University, Rome, Italy. Dr Picconi has spent much of her career studying the alterations of synaptic plasticity in different models of neurodegenerative disorders, particularly in Parkinson's. Her research has focused on the study of the molecular and ...

OPDC Research Day - Oct 2 2018

OPDC Research Day - Oct 2 2018

Posted 13/02/2015

The 2018 OPDC Research Day will be held in the Medical Sciences Teaching Centre, Oxford. The day will start at 9am with a day of talks and  poster sessions on Parkinson's research. This will be followed by a drinks reception from 5-7pm. Attendance is free, but registration is required via our research day website. Abstract Submission closes Friday September 14th 2018  

 

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