The work at Oxford Parkinson's Disease Centre, University of Oxford was featured on the BBC Oxford News. Researchers at the Centre say they are making rapid progress towards detecting the early signs of Parkinson's through the use of MRI scans. Spotting the signs quickly could lead to better treatment and management of the disease. Dr Michele Hu and Dr Richard-Wade Martins of the Centre are interviewed.
OPDC researchers have developed a new genetic mouse model of Parkinson's to track the earliest changes that take place in the brain. The knowledge gained from their groundbreaking study, published in the leading scientific journal PNAS, could pave the way for new treatments that can slow or stop Parkinson's in its tracks. This study is the first to show that the way the chemical messenger dopamine is stored and released is affected at the very start of the process – before Lewy bodies appear.
Congratulations Nahid Zokaei and Rosalind Roberts for winning the first and second poster prizes at the Oxford Parkinson's Research Day! Poster prizes Nahid Zokaei (first):Working memory impairments in Gaucher's disease patients and Parkinson's diease Rosalind Roberts (second): A novel method to detect alpha-synuclein oligomers in Parkinson's disease brain Thank you R&D Systems Europe Ltd for sponsoring the poster prizes and for organising a ...
Scientists at OPDC are genetically engineering brain cells so that they respond to light to investigate why cells stop working as Parkinson's disease progress. Dr Sarah Threlfell, OPDC Career Development Fellow, was interviewed by the BBC News about her Parkinson's UK-funded optogenetics work.
Why are researchers punching into people’s skin if they are on a quest for knowledge about the brain? What does the birth of new brain cells do for memory? Plus can a ‘tumour paint’ be developed to help beat brain cancer? And can we shed those post Christmas extra inches by doing difficult maths problems, instead of hitting the treadmill?
University of Oxford is the academic lead institution for StemBANCC. This 5 year project, which involves academic and industry partners across 11 countries, brings together internationally renowned scientists and clinicians to study and develop new therapies for 8 major diseases of our time: Alzheimer’s, Parkinson’s, Autism, Schizophrenia, Bipolar, Migraine, Pain and Diabetes. Its objective is to develop human-induced pluripotent stem cells as a platform for drug discovery.
OPDC have pioneered a technique that turns pieces of skin into pieces of brain. It's part of a large scale study to create a "bank" of artificially grown brain cells. This BBC news video explains more.
OPDC have begun creating a bank of artificially grown brain cells from Parkinson's patients which will enable researchers to study how the disease develops in unprecedented detail. They are using a new stem cell technique that allows them to turn a small piece of skin from the patient into a small piece of brain. This is the first time this has been done in a large-scale study aimed at finding cures for Parkinson's.
OPDC researchers have succeeded in using stem cell technology to grow nerve cells in the laboratory from initial skin samples taken from people with Parkinson’s. It’s the first large-scale effort of its kind in the UK.
We are looking for up to 300 male volunteers, ideally aged between 50 and 75, who are healthy with no family history of Parkinson’s. Ideally they should be English speaking with no sleep or memory issues. The study is investigating whether it is possible to detect and diagnose Parkinson’s earlier. It is running for the next five years. Dr Michele Hu, cohort study lead said: “One of the earliest phases of Parkinson’s, what we call the prodromal ...