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Multi-Year Collaboration to Advance the Development of Deubiquitinating Enzyme (DUB) Inhibitors for the Treatment of Neurodegenerative Diseases

Multi-Year Collaboration to Advance the Development of Deubiquitinating Enzyme (DUB) Inhibitors for the Treatment of Neurodegenerative Diseases

Posted 10/05/2018

FORMA Therapeutics, the OPDC, and the Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) at Oxford University announced today they have entered into a collaboration and license agreement to identify, validate and develop deubiquitinating enzyme (DUB) inhibitors for the treatment of neurodegenerative diseases. DUBs are a family of over a hundred proteases that play important roles in protein and cellular homeostasis, processes that ...

Jonathan's Big Beautiful Wall Walk

Jonathan's Big Beautiful Wall Walk

Posted 09/05/2018

Jonathan Bromley, member of the Oxford branch of Parkinson's UK will be walking the length of Hadrians Wall over 5 days in June to raise money for Parkinson's UK. Jonathan's wife Sally (Chair of Oxford Parkinson's UK) was diagnosed with Parkinson's in 2008. Since then she has thrown herself wholeheartedly into fundraising and Parkinson's support work, and Jonathan thought it was about time he made a contribution too. I'm not roughing it ...

Students ‘meet the scientists’ at Dunn School

Students ‘meet the scientists’ at Dunn School

Posted 02/05/2018

As part of Science Experience Week organised by Science Oxford, students from three Oxfordshire secondary schools visited research-based organisations and faculties across the region to explore what a science-based career involves. One of their ‘experiences’ was to visit the University of Oxford’s Sir William Dunn School of Pathology to meet the resident scientists and learn about stem cell research. The students, from Matthew Arnold School, ...

OPDC's Professor Peter Magill and Dr Paul Dodson chosen as a focus of new Parkinson's UK fundraising appeal.

OPDC's Professor Peter Magill and Dr Paul Dodson chosen as a focus of new Parkinson's UK fundraising appeal.

Posted 24/04/2018

A new Parkinson's research project, led by OPDC scientists Professor Peter Magill and Dr Paul Dodson, was recently chosen by the charity Parkinson’s UK as a focus of its new fundraising appeal. As part of supporting the appeal, Peter hosted staff and lay members of Parkinson’s UK for a visit to the MRC Brain Network Dynamics Unit. Peter gave a tour of Unit labs and equipment, and was also interviewed about the science underpinning the new ...

Researchers develop a stem cell-based model of mitochondrial disease

Researchers develop a stem cell-based model of mitochondrial disease

Posted 09/04/2018

Mitochondria are the energy-producing factories inside cells. Sometimes genetic mutations can cause these factories to go wrong, leading to a number of neurological diseases. The same genetic mutation affecting mitochondrial function can result in a specific deficit such as loss of vision or a more complicated disorder such as Parkinson’s-like disease.  It is not yet known why the same mutation can have such varying effects. One gene that ...

Brain Awareness Week 2018

Brain Awareness Week 2018

Posted 23/03/2018

March 12-16th 2018 marked Brain Awareness Week with neuroscientists meeting the public to talk about research. OPDC's Imaging lead Professor Clare Mackay and Masud Husain, Professor of Neurology and Cognitive Neuroscience, spoke at a talk open to all about "New developments in Parkinson’s and Alzheimer’s research". In this accessible and informative public talk they explored the latest research into the debilitating neurodegenerative ...

Running for research

Running for research

Posted 19/02/2018

Huge congratulations are in order for DPhil Student Rebecca Wallings, who completed the Dorney Lake Winter Half-Marathon this weekend, in order to raise money for Parkinson’s UK. Becky is a researcher in Richard Wade-Martin’s lab where she is trying to understand what role LRRK2 plays in Parkinson's. Becky had signed up to the Windsor Half-Marathon, but the event was cancelled due to the snow. Becky finished the race in an impressive 2hrs 9 ...

A scientist’s week in Westminster

A scientist’s week in Westminster

Posted 19/12/2017

Professor Peter Magill, OPDC Theme 3 co-lead and Deputy Director of the MRC Brain Network Dynamics Unit at the University of Oxford, gives his account of a week of science and policy in Westminster as he began his participation in The Royal Society’s Pairing Scheme. Once a year, around 30 scientists are paired up with UK parliamentarians and civil servants by the Royal Society, to foster interactions and mutual understanding between researchers ...

OPDC Supporter launches Children's Book

OPDC Supporter launches Children's Book

Posted 17/11/2017

Roberta (Bobbie) Coelho is a member of the Andover Branch of Parkinson's UK and has already co-raised over £17,000 since 2003 for Parkinson's research. Bobbie who has already published a number of poetry books, has decided to try her hand at children's writing and has produced a 13-page children's book which tells the tale of Little Roger the dinosaur, who is fed up of lighting barbeques and sets off on an adventure. Copies of Little Roger's ...