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Mission Therapeutics and OPDC PI Richard Wade-Martins awarded research grant from the Michael J. Fox Foundation

Mission Therapeutics and OPDC PI Richard Wade-Martins awarded research grant from the Michael J. Fox Foundation

Posted 11/04/2017

Mission Therapeutics, a drug discovery and development company focused on selectively targeting deubiquitylating enzymes (DUBs) to treat neurodegenerative diseases, cancer and other diseases with high unmet medical need, announced that it has been awarded a grant from the Michael J. Fox Foundation for Parkinson’s Research (MJFF). This research grant, announced on World Parkinson’s day, will support the testing of Mission Therapeutics’ potent ...

OPDC Investigator heads up new consortium to investigate aggregated proteins in Alzheimer’s and Parkinson’s

OPDC Investigator heads up new consortium to investigate aggregated proteins in Alzheimer’s and Parkinson’s

Posted 10/04/2017

The Innovative Medicines Initiative (IMI) launched IMPRiND in March 2017, an innovative research project that is devoted to investigating whether mechanisms of propagation of aggregated proteins between cells could enable novel therapeutic approaches in Alzheimer’s and Parkinson’s. Alzheimer’s and Parkinson’s are age-related neurodegenerative disorders without cure. They are characterised by the progressive loss of brain cells often along ...

Monique from our OPDC cohort on her experiences

Monique from our OPDC cohort on her experiences

Posted 09/02/2017

Here OPDC participant talks about why being part of such a vast project is very exciting.

"At a time in my life when I cannot do what I used to, taking part in health research gives me a sense of purpose and of still belonging to society and playing my part. It keeps my brain going and gives me hope that one day other people like us, their families and friends will benefit from the results. I have no doubt participating in these studies has helped my confidence"
New way of repurposing drugs could lead to better Parkinson’s treatments

New way of repurposing drugs could lead to better Parkinson’s treatments

Posted 19/01/2017

By bringing together cutting-edge stem cell technologies and computational biology, researchers at OPDC have developed a unique way to identify existing drugs that could potentially be repurposed for treating Parkinson’s. This promising research, published in the journal Human Molecular Genetics, uses a stem cell technique to turn a small piece of skin from people with Parkinson’s into dopamine-producing brain cells – identical to those that ...

OPDC researchers in new drug trial for Parkinson's

OPDC researchers in new drug trial for Parkinson's

Posted 12/01/2017

Our researchers have been granted 600K euros from EU’s Horizon 2020 Framework Programme to join in a multi-centre initiative studying a new drug for Parkinson’s.  The three-year project for Laura Parkkinen’s group is part of the first clinical study of CDNF (Cerebral Dopamine Neurotrophic Factor) in Parkinson's. CDNF, patented worldwide by Herantis Pharma, a Finnish pharmaceutical company, will be administered directly into the brains of 18 ...

OPDC researchers on BBC news

OPDC researchers on BBC news

Posted 15/12/2016

OPDC Clinical Research Fellow Dr Tom Barber recently spoke with BBC Oxford's David Prever about his research into REM sleep behaviour disorder (RBD) and the need to more people to join our study. REM sleep disorder is a condition where people act out nightmares in their sleep. Dr Barber discusses the need for more people with the sleep disorder to join our study and also how we are in need of healthy male volunteers over 50 to join as a control ...

Award for Paul Mayhew Archer's documentary 'the funny side of Parkinson's' featuring OPDC research

Award for Paul Mayhew Archer's documentary 'the funny side of Parkinson's' featuring OPDC research

Posted 09/11/2016

Paul Mayhew-Archer has been named best presenter at the Grierson Awards, which celebrate Britain’s best documentaries. 

Parkinson's: The Funny Side was a rare venture in front of the camera for the man who has written on Miranda, My Hero and Mrs Brown's Boys, as well as The Vicar of Dibley with Richard Curtis. The programme features Dr Fahd Baig, OPDC Clinical Research Fellow, talking to Paul about the phone app that is used in our large Discovery Cohort Study, and Professor Richard Wade-Martins, OPDC Principal Investigator, giving a summary of our research at the OPDC.

Nature Special Issue on Parkinson's showcases OPDC research

Nature Special Issue on Parkinson's showcases OPDC research

Posted 03/11/2016

It is 200 years since Parkinson’s was first described. This special issue from scientific journal Nature charts the progress of research in an engaging timeline and shows how our understanding of Parkinson’s motor and non-motor symptoms has evolved. It also reveals the exciting new applications of smartphones in monitoring the disease including the pioneering research being carried out by OPDC researchers including Max Little. OPDC participants ...

OPDC PIs among project leads for Oxford Momentum Award

OPDC PIs among project leads for Oxford Momentum Award

Posted 27/10/2016

Six universities including Oxford have been awarded a total of £4.3m by the Medical Research Council (MRC) to grow and develop the UK’s research base in dementia science.

The Momentum awards, designed to support the UK Dementia Research Institute (DRI), will help open new research avenues which could transform the potential of dementia research in the UK. The awards represent the first steps in establishing the capabilities for the DRI, which is being funded through a combined investment of £250m from the MRC and founding charity partners, the Alzheimer’s Society and Alzheimer’s Research UK. The DRI is expected to be up and running by 2019. Project leads for this multi-disciplinary programme include OPDC's Sally Cowley and Caleb Webber.

Team OPDC at Oxford Parkinson's Walk 2016

Team OPDC at Oxford Parkinson's Walk 2016

Posted 24/10/2016

Despite a very soggy start to the day there was a brilliant turnout for the 2016 Oxford Parkinson's Walk on October 16th. The event, organised by the Oxford branch of Parkinson's UK, raises funds to support research here at OPDC.  This year the funds are to be directed to Steph Cragg's GABA project looking at alternatives to dopamine. Steph Cragg started the walkers this year and after a great countdown the crowd took to the road as thankfully ...