The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.
Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.
Our programme targets the molecular pathways to Parkinson’s in order to:
Rolinski M, Griffanti L, Piccini P, Roussakis AA, Szewczyk-Krolikowski K, Menke RA, Quinnell T, Zaiwalla Z, Klein JC, Mackay CE, Hu MT. (2016) Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson's disease. Brain. PMID: 27297241
Baig F, Lawton MA, Rolinski M, Ruffmann C, Klein JC, Nithi K, Okai D, Ben-Shlomo Y, Hu MTM. (2017) Personality and addictive behaviours in early Parkinson’s disease and REM sleep behavior disorder. Park Rel Dis. 37:72-78. PMID:28173973
Researchers in the Oxford Parkinson’s Disease Centre are embarking on a new five-year study looking at the links between a condition known as Rapid Eye Movement Sleep Behaviour Disorder (RBD) and Parkinson’s. Funded by the NIHR Oxford Biomedical Research Centre, the study seeks to improve the remote diagnosis and monitoring of sleep problems at home.
FORMA Therapeutics, the OPDC, and the Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) at Oxford University announced today they have entered into a collaboration and license agreement to identify, validate and develop deubiquitinating enzyme (DUB) inhibitors for the treatment of neurodegenerative diseases. DUBs are a family of over a hundred proteases that play important roles in protein and cellular homeostasis, processes that ...
Sally Bromley, chair of Parkinson's UK Oxford and much valued supporter of OPDC, has been bestowed with an honorary degree.
The Open University has officially awarded Sally Bromley the certificate, in recognition of her role supporting medical studies and helping other people with Parkinson's.
Mrs Bromley co-wrote the First Steps programme to help others through diagnosis, a workshop which helps people to come to terms with the condition.
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Mitophagy modulation as a potential therapeutic target for neurodegenerative diseases UCL Institute of Neurology In recent years, it has become clear that even in clinically distinct neurodegenerative conditions, there are common underlying themes in how the neurons become sick and die. One such theme is a breakdown in the maintenance of mitochondria, which plays a central role in Parkinson’s disease and in other neurodegenerative ...
The annual Oxford Dementia Research Day at St John's College Oxford is jointly organised by NIHR Oxford Health Biomedical Research Centre and Alzheimer's Research UK Oxford Local Network. This free meeting will include a full day of talks covering subjects including cellular and clinical research, managing dementia and cognition. There will also be poster sessions through the day with plenty of time for networking and an evening reception. Click for details including how to register