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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
Watch the video below to see OPDC's Michele Hu talk about our research at Parkinson's UK's Bespoke Treatment Lectures at the Royal Institution.



Peter’s Parkinson’s Pilgrimage

Peter’s Parkinson’s Pilgrimage

Posted 04/01/2016

A participant from our Monument Discovery Project, Peter Charles, who has been taking part in our research study for the last four years, is going to embark on an incredible fundraising walk in February. The walk will take him from Little Missenden, Buckinghamshire to Santiago de Compostela in Spain, totalling more than 1,500 miles. Peter aims to raise £250,000 for Parkinson’s UK, which will be split 90% towards finding a cure for Parkinson’s an ...

Protein-protein interaction networks in a model of Parkinson's disease.

Protein-protein interaction networks in a model of Parkinson's disease.

Posted 09/12/2015

New paper published in Scientific Reports by Brent Ryan and Harriet Keane in the Wade-Martins Lab.  We created a network showing how proteins that are important in a model of Parkinson’s disease talk to (interact with) each other. We then mathematically analysed this network to determine which proteins were the most important for linking important cellular processes in Parkinson’s. Based on these mathematical predictions, we then tested if we co ...


Miquel Vila Seminar: 16th February

Miquel Vila Seminar: 16th February

Posted 01/07/2015

Professor Miquel Vila ICREA Research Professor and  Associate Professor Department of Biochemistry and Molecular Biology, Autonomous University of Barcelona (UAB) Professor Vila's research is geared toward elucidating the molecular mechanisms of neuron cell death occurring in Parkinson’s disease, a particular neurodegenerative disorder characterized by the degeneration of a specific set of neurons that are anatomically confined to a region of t ...

Malin Parmar Seminar: 15th March

Malin Parmar Seminar: 15th March

Posted 13/02/2015

Professor Malin Parmar  Title: "Translational stem cell biology: Developing Cell Therapy for Parkinson's Disease" 15th March 2016, 3pm, Library, Sherrington Building   Associate Professor, Lund University    Professor Malin Parmar's group works with translational stem cell biology. The focus of her research is to understand cell fate specification in the developing brain and in human neural progenitor cells using cell-based models of neur ...

Selected Publications

Med Sci