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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
  • Watch the video below to learn more about OPDC's research

 

Selected Publications

News

Major new study launched to investigate the link between sleep problems and Parkinson’s

Major new study launched to investigate the link between sleep problems and Parkinson’s

Posted 13/07/2018

Researchers in the Oxford Parkinson’s Disease Centre are embarking on a new five-year study looking at the links between a condition known as Rapid Eye Movement Sleep Behaviour Disorder (RBD) and Parkinson’s. Funded by the NIHR Oxford Biomedical Research Centre, the study seeks to improve the remote diagnosis and monitoring of sleep problems at home.


Multi-Year Collaboration to Advance the Development of Deubiquitinating Enzyme (DUB) Inhibitors for the Treatment of Neurodegenerative Diseases

Multi-Year Collaboration to Advance the Development of Deubiquitinating Enzyme (DUB) Inhibitors for the Treatment of Neurodegenerative Diseases

Posted 10/05/2018

FORMA Therapeutics, the OPDC, and the Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) at Oxford University announced today they have entered into a collaboration and license agreement to identify, validate and develop deubiquitinating enzyme (DUB) inhibitors for the treatment of neurodegenerative diseases. DUBs are a family of over a hundred proteases that play important roles in protein and cellular homeostasis, processes that ...


Congratulations from all at OPDC to Sally Bromley, chair of Parkinson's UK Oxford, on her honorary degree

Congratulations from all at OPDC to Sally Bromley, chair of Parkinson's UK Oxford, on her honorary degree

Posted 13/07/2018

Sally Bromley, chair of Parkinson's UK Oxford and much valued supporter of OPDC, has been bestowed with an honorary degree.

The Open University has officially awarded Sally Bromley the certificate, in recognition of her role supporting medical studies and helping other people with Parkinson's.

Mrs Bromley co-wrote the First Steps programme to help others through diagnosis, a workshop which helps people to come to terms with the condition.

 

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Seminars/Events

Hélène Plun-Favreau - 13 June 2018

Hélène Plun-Favreau - 13 June 2018

Posted 21/03/2018

Mitophagy modulation as a potential therapeutic target for neurodegenerative diseases UCL Institute of Neurology In recent years, it has become clear that even in clinically distinct neurodegenerative conditions, there are common underlying themes in how the neurons become sick and die. One such theme is a breakdown in the maintenance of mitochondria, which plays a central role in Parkinson’s disease and in other neurodegenerative ...

Oxford Dementia Research Day, Thursday 12th July 2018

Oxford Dementia Research Day, Thursday 12th July 2018

Posted 08/06/2018

The annual Oxford Dementia Research Day at St John's College Oxford is jointly organised by NIHR Oxford Health Biomedical Research Centre and Alzheimer's Research UK Oxford Local Network. This free meeting will include a full day of talks covering subjects including cellular and clinical research, managing dementia and cognition. There will also be poster sessions through the day with plenty of time for networking and an evening reception. Click for details including how to register

 

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