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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
  • Watch the video below to learn more about OPDC's research

 

Selected Publications

News

Going Viral

Going Viral

Posted 28/09/2016

Viruses have been a threat to humanity for as long as we have existed. As we make progress in the fight against them, can we also learn to use their tricks to our own advantage. This new podcast in the Oxford Biomedical Research series features Professor Magill and colleagues from the  MRC Brain Networks Dynamics Unit at the University of Oxford. Listen to MRC BMDU scientists talk about the use of viruses in brain research here

OPDC collaboration finds Parkinson's protein test which could lead to earlier diagnosis

OPDC collaboration finds Parkinson's protein test which could lead to earlier diagnosis

Posted 31/08/2016

Scientists from the Oxford Parkinson’s Disease Centre (OPDC) together with Edinburgh Prion Unit have developed a new diagnostic test for Parkinson’s that measures the “stickiness” of alpha-synuclein; one of the key proteins in Parkinson's, in the cerebrospinal fluid (CSF). This same protein forms sticky clumps known as Lewy bodies within the brain cells of people with Parkinson's and dementia with Lewy bodies (DLB). There is currently no ...

Andover OPDC supporters raise more funds

Andover OPDC supporters raise more funds

Posted 12/08/2016

OPDC supporters Bobbie Coelho, Mary Doherty and Dawn Huntley were amongst a team in Andover who work tirelessly raising funds for our research. The team organise a range of fundraising activities including collecting donated items which they sell at car boot sales.  Bobbie is also donating profits from the sale of her poetry books, Reflecting the Light  and Finding the Light, to fund Parkinson's research. Watch Bobbie performing her poem "In ...

Thames Valley Regional Meeting Update: June 2016

Thames Valley Regional Meeting Update: June 2016

Posted 05/08/2016

The latest newsletter from the Thames Valley Excellence Network (TVEN), led by OPDC's Dr Michele Hu, is now available online here. It reports on the network meeting, discusses mental health issues in Parkinson's, updates on the First Steps programme for those just diagnosed with Parkinson's and highlights  research opportunities with OPDC. It also features Ewan Stutt from the younger onset Parkinson's group and founder of the Parkinsons.me ...

Seminars/Events

John Reynolds Seminar - 27 Sept 2016

John Reynolds Seminar - 27 Sept 2016

Posted 28/06/2016

His research team studies the application of neuroplasticity approaches to Parkinson’s disease and stroke. His interest is in applying the principles of neuromodulation to modify synaptic plasticity and recover function in affected brain areas.  The primary focus of his research is on learning and movement generation processes in the basal ganglia and cerebral cortex. In the basal ganglia the emphasis is on unraveling the normal role of ...

Mickael Decressac: 15 Nov 2016

Mickael Decressac: 15 Nov 2016

Posted 21/06/2016

Mickael Decressac's lab at the Telethon Institute of Genetics and Medicine (TIGEM) aims to identify potential therapeutic targets of Parkinson's, validate them in relevant and complementary models of the condition, and finally, design clinically relevant strategies in order to bring them to the bedside. In 2012, he developed a viral vector-based model of Parkinson’s, which is widely used for studying the pathological mechanisms and testing ...

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