Research Banner Thierry

About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
  • Watch the video below to learn more about OPDC's research


Selected Publications


Healthy males needed for our study

Healthy males needed for our study

Posted 09/12/2016

We are looking for up to 300 male volunteers, ideally aged between 50 and 75, who are healthy with no family history of Parkinson’s. Ideally they should be English speaking with no sleep or memory issues. The study is investigating whether it is possible to detect and diagnose Parkinson’s earlier. It is running for the next five years. Dr Michele Hu, cohort study lead said: “One of the earliest phases of Parkinson’s, what we call the prodromal ...

Monique from our OPDC cohort on her experiences

Monique from our OPDC cohort on her experiences

Posted 09/02/2017

Here OPDC participant talks about why being part of such a vast project is very exciting.

"At a time in my life when I cannot do what I used to, taking part in health research gives me a sense of purpose and of still belonging to society and playing my part. It keeps my brain going and gives me hope that one day other people like us, their families and friends will benefit from the results. I have no doubt participating in these studies has helped my confidence"
New way of repurposing drugs could lead to better Parkinson’s treatments

New way of repurposing drugs could lead to better Parkinson’s treatments

Posted 19/01/2017

By bringing together cutting-edge stem cell technologies and computational biology, researchers at OPDC have developed a unique way to identify existing drugs that could potentially be repurposed for treating Parkinson’s. This promising research, published in the journal Human Molecular Genetics, uses a stem cell technique to turn a small piece of skin from people with Parkinson’s into dopamine-producing brain cells – identical to those that ...

Click here to sign up to the OPDC News Mailing list


OPDC Parkinson's Research Day

OPDC Parkinson's Research Day

Posted 16/02/2017

OPDC Parkinson's Research Day 20th March 2017

The OPDC Research Day is a one-day event with research talks from world leading Parkinson’s researchers on topics including clinical studies, imaging, genetics, proteomics, neuronal cells and animal models.

  • The 2017 OPDC Research Day will be held in the Medical Sciences Teaching Centre, Oxford
  • The day will start at 9am with a programme of talks and poster sessions on Parkinson's research. This will be followed by a drinks reception from 5-7pm. Click here to register for your free place.
  • This one-day event will include research talks by national and international keynote speakers and Oxford researchers on a range of Parkinson’s work including clinical studies, imaging, genetics, proteomics, neuronal cell culture and animal models.
Beate Ritz - 25 April 2017

Beate Ritz - 25 April 2017

Posted 30/09/2016

Professor Beate Ritz joined the faculty of the School of Public Health at UCLA in 1995 and is currently Professor and Vice Chair of the Epidemiology Department and holds co-appointments in the Environmental Health department at the UCLA School of Public Health and in Neurology, UCLA School of Medicine. Her research focuses on the health effects of occupational and environmental toxins such as pesticides, ionizing radiation, and air pollution on ...

Med Sci