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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
  • Watch the video below to learn more about OPDC's research

 

Selected Publications

News

Healthy males needed for our study

Healthy males needed for our study

Posted 09/12/2016

We are looking for up to 300 male volunteers, ideally aged between 50 and 75, who are healthy with no family history of Parkinson’s. Ideally they should be English speaking with no sleep or memory issues. The study is investigating whether it is possible to detect and diagnose Parkinson’s earlier. It is running for the next five years. Dr Michele Hu, cohort study lead said: “One of the earliest phases of Parkinson’s, what we call the prodromal ...


New way of repurposing drugs could lead to better Parkinson’s treatments

New way of repurposing drugs could lead to better Parkinson’s treatments

Posted 19/01/2017

By bringing together cutting-edge stem cell technologies and computational biology, researchers at OPDC have developed a unique way to identify existing drugs that could potentially be repurposed for treating Parkinson’s. This promising research, published in the journal Human Molecular Genetics, uses a stem cell technique to turn a small piece of skin from people with Parkinson’s into dopamine-producing brain cells – identical to those that ...


OPDC researchers in new drug trial for Parkinson's

OPDC researchers in new drug trial for Parkinson's

Posted 12/01/2017

Our researchers have been granted 600K euros from EU’s Horizon 2020 Framework Programme to join in a multi-centre initiative studying a new drug for Parkinson’s.  The three-year project for Laura Parkkinen’s group is part of the first clinical study of CDNF (Cerebral Dopamine Neurotrophic Factor) in Parkinson's. CDNF, patented worldwide by Herantis Pharma, a Finnish pharmaceutical company, will be administered directly into the brains of 18 ...

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Seminars/Events

Kostas Vekrellis - 14 Feb 2017

Kostas Vekrellis - 14 Feb 2017

Posted 30/09/2016

Since 2002 Dr. Vekrellis has been a Researcher in the Division of Basic Neurosceiences at the Biomedical Research Foundation of the Academy of Athens (BRFAA). In April 2012, he was appointed a visiting professorship at the  the University of Oxford, Division of Exerimental Medicine, Nuffield department of Medicine. Dr. Vekrellis has extensive experience in cellular and animal models of neurodegeneration, as well as human histopathology, ...

Beate Ritz - 25 April 2017

Beate Ritz - 25 April 2017

Posted 30/09/2016

Professor Beate Ritz joined the faculty of the School of Public Health at UCLA in 1995 and is currently Professor and Vice Chair of the Epidemiology Department and holds co-appointments in the Environmental Health department at the UCLA School of Public Health and in Neurology, UCLA School of Medicine. Her research focuses on the health effects of occupational and environmental toxins such as pesticides, ionizing radiation, and air pollution on ...

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