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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
  • Watch the video below to learn more about OPDC's research

 

Selected Publications

News

Multi-Year Collaboration to Advance the Development of Deubiquitinating Enzyme (DUB) Inhibitors for the Treatment of Neurodegenerative Diseases

Multi-Year Collaboration to Advance the Development of Deubiquitinating Enzyme (DUB) Inhibitors for the Treatment of Neurodegenerative Diseases

Posted 10/05/2018

FORMA Therapeutics, the OPDC, and the Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) at Oxford University announced today they have entered into a collaboration and license agreement to identify, validate and develop deubiquitinating enzyme (DUB) inhibitors for the treatment of neurodegenerative diseases. DUBs are a family of over a hundred proteases that play important roles in protein and cellular homeostasis, processes that ...


Congratulations to Sally Bromley, chair of Parkinson's UK Oxford on her Honorary degree from all at OPDC

External Link found on http://opdc.medsci.ox.ac.uk/news


Jonathan's Big Beautiful Wall Walk

Jonathan's Big Beautiful Wall Walk

Posted 09/05/2018

Jonathan Bromley, member of the Oxford branch of Parkinson's UK will be walking the length of Hadrians Wall over 5 days in June to raise money for Parkinson's UK. Jonathan's wife Sally (Chair of Oxford Parkinson's UK) was diagnosed with Parkinson's in 2008. Since then she has thrown herself wholeheartedly into fundraising and Parkinson's support work, and Jonathan thought it was about time he made a contribution too. I'm not roughing it ...

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Seminars/Events

Vladyslav Vyazovskiy 16 May 2018

Vladyslav Vyazovskiy 16 May 2018

Posted 21/03/2018

Associate Professor of Neuroscience Sleep, brain and behaviour laboratory In the last decades a vast empirical and theoretical knowledge about sleep mechanisms has been accumulated. Surprisingly, the function of sleep still remains elusive. Moreover, in place of the long-standing question “why do we sleep?” now comes a more fundamental one: “what is sleep?” Among the key features of sleep are: a) the occurrence of slow waves in NREM sleep ...

Hélène Plun-Favreau - 13 June 2018

Hélène Plun-Favreau - 13 June 2018

Posted 21/03/2018

Mitophagy modulation as a potential therapeutic target for neurodegenerative diseases UCL Institute of Neurology In recent years, it has become clear that even in clinically distinct neurodegenerative conditions, there are common underlying themes in how the neurons become sick and die. One such theme is a breakdown in the maintenance of mitochondria, which plays a central role in Parkinson’s disease and in other neurodegenerative ...

 
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