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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
  • Watch the video below to learn more about OPDC's research

 

Selected Publications

News

Award for Paul Mayhew Archer's documentary 'the funny side of Parkinson's' featuring OPDC research

Award for Paul Mayhew Archer's documentary 'the funny side of Parkinson's' featuring OPDC research

Posted 09/11/2016

Paul Mayhew-Archer has been named best presenter at the Grierson Awards, which celebrate Britain’s best documentaries. 

Parkinson's: The Funny Side was a rare venture in front of the camera for the man who has written on Miranda, My Hero and Mrs Brown's Boys, as well as The Vicar of Dibley with Richard Curtis. The programme features Dr Fahd Baig, OPDC Clinical Research Fellow, talking to Paul about the phone app that is used in our large Discovery Cohort Study, and Professor Richard Wade-Martins, OPDC Principal Investigator, giving a summary of our research at the OPDC.


Nature Special Issue on Parkinson's showcases OPDC research

Nature Special Issue on Parkinson's showcases OPDC research

Posted 03/11/2016

It is 200 years since Parkinson’s was first described. This special issue from scientific journal Nature charts the progress of research in an engaging timeline and shows how our understanding of Parkinson’s motor and non-motor symptoms has evolved. It also reveals the exciting new applications of smartphones in monitoring the disease including the pioneering research being carried out by OPDC researchers including Max Little. OPDC participants ...


OPDC PIs among project leads for Oxford Momentum Award

OPDC PIs among project leads for Oxford Momentum Award

Posted 27/10/2016

Six universities including Oxford have been awarded a total of £4.3m by the Medical Research Council (MRC) to grow and develop the UK’s research base in dementia science.

The Momentum awards, designed to support the UK Dementia Research Institute (DRI), will help open new research avenues which could transform the potential of dementia research in the UK. The awards represent the first steps in establishing the capabilities for the DRI, which is being funded through a combined investment of £250m from the MRC and founding charity partners, the Alzheimer’s Society and Alzheimer’s Research UK. The DRI is expected to be up and running by 2019. Project leads for this multi-disciplinary programme include OPDC's Sally Cowley and Caleb Webber.

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Seminars/Events

Nick Allen - Dec 8th

Nick Allen - Dec 8th

Posted 30/09/2016

Nick Allen is Professor of Stem Cell Science at Cardiff University's School of Biosceinces.  Professor Allen's research focuses on the mechanisms of neural differentiation of human and mouse embryonic stem cells with the aim of developing protocols to direct the differentiation of neural progenitors to acquire specific neural fates and phenotypes. His research projects include: Neural differentiation of human and mouse embryonic stem ...

Beth Cimini 14 Dec 2016

Beth Cimini 14 Dec 2016

Posted 27/10/2016

  Beth Cimini is a postdoctoral fellow and assay developer in Dr. Anne Carpenter's lab at the Broad Institute.  Beth graduated magna cum laude with BA from Boston University, where she studyied cholinergic stimulation of nitric oxide production in the salamander retina.  She went on to do her PhD at University of California-San Francisco under Dr. Elizabeth Blackburn, where she focused on the physiological roles of different isoforms of the ...

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