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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
Watch the video below to see OPDC's Michele Hu talk about our research at Parkinson's UK's Bespoke Treatment Lectures at the Royal Institution.



OPDC PIs visit Luxembourg to start collaboration

OPDC PIs visit Luxembourg to start collaboration

Posted 29/07/2015

During their visit and lectures at the Luxembourg Centre for Systems Biomedicine (LCSB), OPDC PIs Michele Hu and Richard Wade-Martins exchanged their experiences from the last five years with researchers from Luxembourg and started a collaboration with the National Centre of Excellence in Research on Parkinson’s disease (NCER-PD). The NCER-PD has set itself the aim of finding new ways for an earlier diagnosis and better treatment for ...

2015 OPDC Newsletter

2015 OPDC Newsletter

Posted 22/06/2015

This bumper issue of the OPDC newsletter celebrates our funding renewal. As well as an update on how our cohort is doing, the newsletter includes news on our research linking Parkinson's and sleep disorders, how imaging can help detect early signs of Pakrinson's and how we are using blood samples to try to find biomarkers for early diagnosis. You can also read about OPDC's role in the new MRC Dementias Platform UK (DPUK) and the Alzheimer's ...


Professor Malin Parmar "Translational stem cell biology: Developing Cell Therapy for Parkinson's Disease"

Professor Malin Parmar "Translational stem cell biology: Developing Cell Therapy for Parkinson's Disease"

Posted 13/02/2015

Professor Malin Parmar "Translational stem cell biology: Developing Cell Therapy for Parkinson's Disease" This talk has been postponed untill Autumn 2015   Associate Professor, Lund University     Professor Malin Parmar's group works with translational stem cell biology. The focus of her research is to understand cell fate specification in the developing brain and in human neural progenitor cells using cell-based models of neuronal ...

Giovanna Mallucci - 24 Nov 2015

Giovanna Mallucci - 24 Nov 2015

Posted 01/07/2015

Professor Giovanna Mallucci is Programme Leader at the MRC Toxicology Unit, University of Leicester. Her research group works on mechanisms of neurotoxicity. Her background is in modelling prion diseases in mice, looking at mechanisms of neurotoxicity and developing new therapeutic approaches. Her group have shown that early synaptic changes in mice with prion disease can be reversed, resulting in recovery of synaptic and cognitive function ...

Selected Publications

Med Sci