The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.
Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.
Our programme targets the molecular pathways to Parkinson’s in order to:
Rolinski M, Griffanti L, Piccini P, Roussakis AA, Szewczyk-Krolikowski K, Menke RA, Quinnell T, Zaiwalla Z, Klein JC, Mackay CE, Hu MT. (2016) Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson's disease. Brain. PMID: 27297241
Baig F, Lawton MA, Rolinski M, Ruffmann C, Klein JC, Nithi K, Okai D, Ben-Shlomo Y, Hu MTM. (2017) Personality and addictive behaviours in early Parkinson’s disease and REM sleep behavior disorder. Park Rel Dis. 37:72-78. PMID:28173973
FORMA Therapeutics, the OPDC, and the Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) at Oxford University announced today they have entered into a collaboration and license agreement to identify, validate and develop deubiquitinating enzyme (DUB) inhibitors for the treatment of neurodegenerative diseases. DUBs are a family of over a hundred proteases that play important roles in protein and cellular homeostasis, processes that ...
External Link found on http://opdc.medsci.ox.ac.uk/news
Jonathan Bromley, member of the Oxford branch of Parkinson's UK will be walking the length of Hadrians Wall over 5 days in June to raise money for Parkinson's UK. Jonathan's wife Sally (Chair of Oxford Parkinson's UK) was diagnosed with Parkinson's in 2008. Since then she has thrown herself wholeheartedly into fundraising and Parkinson's support work, and Jonathan thought it was about time he made a contribution too. I'm not roughing it ...
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Mitophagy modulation as a potential therapeutic target for neurodegenerative diseases UCL Institute of Neurology In recent years, it has become clear that even in clinically distinct neurodegenerative conditions, there are common underlying themes in how the neurons become sick and die. One such theme is a breakdown in the maintenance of mitochondria, which plays a central role in Parkinson’s disease and in other neurodegenerative ...
The annual Oxford Dementia Research Day at St John's College Oxford is jointly organised by NIHR Oxford Health Biomedical Research Centre and Alzheimer's Research UK Oxford Local Network. This free meeting will include a full day of talks covering subjects including cellular and clinical research, managing dementia and cognition. There will also be poster sessions through the day with plenty of time for networking and an evening reception. Click for details including how to register
© 2018 Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics, Le Gros Clark Building, South Parks Road, Oxford, OX1 3QX
Tel: 01865 282358 | Enquiries: opdc.administrator@dpag.ox.ac.uk
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