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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
Watch the video below to see OPDC's Michele Hu talk about our research at Parkinson's UK's Bespoke Treatment Lectures at the Royal Institution.

 

News

OPDC develop new method to look for Parkinson's Biomarkers

OPDC develop new method to look for Parkinson's Biomarkers

Posted 20/03/2015

The OPDC aims to understand the earliest events that lead to Parkinson’s.  Recently we have made exciting discoveries about the role of alpha-synuclein oligomers in Parkinson’s in a study of post-mortem brain tissue from people with Parkinson’s and healthy controls.    During the development of Parkinson’s the protein alpha-synuclein begins to function abnormally and clumps together to form small clusters, known as oligomers.  Alpha-synuclein ...

OPDC celebrate winning £6M from Parkinson’s UK

OPDC celebrate winning £6M from Parkinson’s UK

Posted 05/03/2015

OPDC celebrate winning £6M from Parkinson’s UK OPDC is celebrating today after Parkinson’s UK awarded £6M to our cutting-edge research programme - allowing our search for a cure for Parkinson’s to continue. By 2020 we hope to use the £6M from Parkinson's UK to find new drugs to slow, or even stop Parkinson’s, using a ‘brain cell bank’ we have developed to identify promising new drug targets. We also want to improve how to diagnose and ...

Seminars/Events

OPDC Research Day - April 20 2015

OPDC Research Day - April 20 2015

Posted 13/02/2015

The 2015 OPDC Research Day will be held in the Mathematical Institute, Oxford. The day will start at 9am with a day of talks and  poster sessions on Parkinson's research. This will be followed by a drinks reception from 5-7pm. Keynote speakers Professor Donald Grosset, Dr Alex Whitworth and Professor Jochen Roeper. Attendance is free, but registration is required by 10th April 2015 via our research day website. Abstract Submission Deadline ...

Professor Steven Gill, May 05, 2015 4-5 PM

Professor Steven Gill, May 05, 2015 4-5 PM

Posted 13/02/2015

Professor Steven Gill Tuesday May 05, 2015 4-5 PM Library, Sherrington Building, DPAG   Professor Steven Gill pioneered the original work using Glial cell line-Derived Neurotrophic Factor (GDNF) in people with Parkinson’s. Since the initial pilot study, he has designed a new delivery system to enable this key growth factor to be delivered optimally, not only in terms of safety and efficacy, but also in a way which can be administered ...

Publications

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