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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
  • Watch the video below to learn more about OPDC's research

 

Selected Publications

News

Parkinson's 200 plus conference by and for people with Parkinson's to take place in Oxford

Parkinson's 200 plus conference by and for people with Parkinson's to take place in Oxford

Posted 20/07/2017

Parkinson’s UK Oxford Branch have announced a major conference for people with Parkinson’s (PwP) to place place in Oxford on Monday 18 September. Leading experts will discuss the latest developments in the four pillars of Parkinson’s treatment – medicines, exercise, life style and mental health ­– which together offer an improved quality of life for PwP.     “The 200th anniversary of James Parkinson’s essay which first described what he ...


OPDC researcher Simon Lovestone knighted in Queen’s Birthday honours

OPDC researcher Simon Lovestone knighted in Queen’s Birthday honours

Posted 22/06/2017

Dr Lovestone is a practising Old Age Psychiatrist who has been recognised for his services to neuroscience research. His research focuses on the regulation of tau phosphorylation, the search for genetic and other biomarkers of Alzheimer’s disease and, building on these, on drug discovery and experimental medicine. Underpinning all these studies is the use of informatics - clinical informatics, bioinformatics and the challenges of extracting ...


OPDC researchers honoured at teaching award ceremony

OPDC researchers honoured at teaching award ceremony

Posted 05/06/2017

Researchers at OPDC were selected as finalists at the 2017 Oxford University Students’ Union Teaching awards.  There were 895 nominations for this year’s awards. Every single nomination highlighted an example of exceptional effort and talent, and every nominee deserves to be recognised for their achievements. Dr Siddharth Arora, who works on OPDC’s smartphone project, was the winner of the Most Acclaimed Lecturer Award for the division of ...

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Seminars/Events

Michela Deleidi July 19 2017

Michela Deleidi July 19 2017

Posted 19/09/2016

Research in Dr Deleidi’s laboratory concentrates on the molecular mechanisms of neurodegeneration, with a special emphasis on the role of inflammation in Parkinson's disease. Neuroinflammatory genes have been associated with several neurodegenerative diseases, including Parkinson's disease. Their aim is to understand, at the molecular level, how disease-associated genetic variants affect immune cell metabolism, and how immune responses within or ...

Kathleen Maguire-Zeiss: 8 Aug Inflammation & Neurodegeneration: a Role for Toll-like Receptors

Kathleen Maguire-Zeiss: 8 Aug Inflammation & Neurodegeneration: a Role for Toll-like Receptors

Posted 03/05/2017

Dr. Maguire-Zeiss' laboratory at Georgtown University aims to understand the molecular mechanisms involved in  progressive neurodegenerative diseases like Parkinson's disease and HAND. The laboratory focuses on glial-directed innate immune responses and the effect of inflammation on neuronal health and function.  By investigating how glial cells respond to chemokines/cytokines and misfolded proteins, specific signaling pathways are identified ...

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