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About us

The Oxford Parkinson's Disease Centre (OPDC) is a unique multidisciplinary research centre at the University of Oxford supported by Parkinson’s UK with funds from The Monument Trust, one of the Sainsbury Family Charitable Trusts.

Established in February 2010, the Oxford Parkinson’s Disease Centre (OPDC) brings together internationally-renowned scientists who work on the genetics of Parkinson’s, the generation of cell and animal models, and the wiring of brain circuits which control movement, with clinical experts in the diagnosis and treatment of Parkinson’s.

Our world-class research centre was formed to understand the earliest events in the development of Parkinson’s and create animal models with greater relevance to the disease, ultimately with a view to identifying the changes which occur before the symptoms become apparent.

Our programme targets the molecular pathways to Parkinson’s in order to:

  1. Understand the progression of Parkinson’s
  2. Predict the onset of Parkinson’s
  3. Identify potential drug targets for Parkinson’s
  4. Develop new treatments that will prevent the development of Parkinson’s in at-risk individuals.
  • Watch the video below to learn more about OPDC's research

 

Selected Publications

News

OPDC researcher Simon Lovestone knighted in Queen’s Birthday honours

OPDC researcher Simon Lovestone knighted in Queen’s Birthday honours

Posted 22/06/2017

Dr Lovestone is a practising Old Age Psychiatrist who has been recognised for his services to neuroscience research. His research focuses on the regulation of tau phosphorylation, the search for genetic and other biomarkers of Alzheimer’s disease and, building on these, on drug discovery and experimental medicine. Underpinning all these studies is the use of informatics - clinical informatics, bioinformatics and the challenges of extracting ...


OPDC researchers honoured at teaching award ceremony

OPDC researchers honoured at teaching award ceremony

Posted 05/06/2017

Researchers at OPDC were selected as finalists at the 2017 Oxford University Students’ Union Teaching awards.  There were 895 nominations for this year’s awards. Every single nomination highlighted an example of exceptional effort and talent, and every nominee deserves to be recognised for their achievements. Dr Siddharth Arora, who works on OPDC’s smartphone project, was the winner of the Most Acclaimed Lecturer Award for the division of ...


OPDC scientist Dr Ludovica Griffanti talks about her research in the pub at sell-out event

OPDC scientist Dr Ludovica Griffanti talks about her research in the pub at sell-out event

Posted 24/05/2017

This May, Dr Ludovica Griffanti was among scientists who spoke at the sell-out Beautiful Minds session at the St Aldates Tavern, Oxford. The event was part of the Pint of Science series which brings some of the most brilliant scientists to local pubs to discuss their latest research and findings. Dr Griffanti is a researcher with OPDC at the Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB). Her talk dealt with her ...

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Seminars/Events

Steven Finkbeiner 13 June 2017

Steven Finkbeiner 13 June 2017

Posted 30/09/2016

Professor Steven Finkbeiner, M.D., Ph.D. is a neurologist and neuroscientist, a professor at the University of California, San Francisco, and associate director at the Gladstone Institutes. He directs an academic research laboratory focused on neurodegenerative diseases and mental illnesses and directs the Taube/Koret Center for Neurological Disease, which focuses on collaborating with industry to develop neurotherapeutics. Dr. Finkbeiner ...

Michela Deleidi July 19 2017

Michela Deleidi July 19 2017

Posted 19/09/2016

Research in Dr Deleidi’s laboratory concentrates on the molecular mechanisms of neurodegeneration, with a special emphasis on the role of inflammation in Parkinson's disease. Neuroinflammatory genes have been associated with several neurodegenerative diseases, including Parkinson's disease. Their aim is to understand, at the molecular level, how disease-associated genetic variants affect immune cell metabolism, and how immune responses within or ...

Med Sci
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